Root bifurcation lesions Periodontal tissue regeneration
Conditions
Interventions
Regenerative medicine
Sponsors
Tobita Morikuni
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Bifurcation lesions and Lindhe and Nyman classification II degree or higher. 2) Basic periodontal treatment has been completed. 3) Subject teeth are less than 2 degrees of mobility and have keratinized gingiva that is considered appropriate for flap surgery. 4) Persons whose oral hygiene is established Good oral hygiene. 5) Have good systemic condition. 6) Number of platelet is over 1x10^5 /microli ter. 7) 18 years and older. 8) Other,the investigator believes makes him/her suitable for participation in the clinical study.
Exclusion criteria
Exclusion criteria: (1) Individuals for whom clinical attachment level measurement of the target tooth is not possible (2) Patients with current or past malignant tumors (3) Individuals with findings suggestive of malignancy, precancerous lesions, or suspected lesions during the pre-registration oral examination (4) Individuals with uncontrolled renal, hepatic, or hematologic disorders (5) Individuals who test positive for HCV antibodies, HBs antigen, ATLA virus antibodies, or HIV antibodies (6) Smokers (those who smoke an average of 10 or more cigarettes per day) (7) Individuals taking anticoagulants and whose blood condition is difficult to manage (8) Patients under the age of 18 (9) Women who wish to conceive, are pregnant or may be pregnant, or are breastfeeding (10) Others deemed inappropriate by the principal investigator due to serious infections or other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy | — |
Countries
Japan
Contacts
Public ContactMorikuni Tobita
untendo Hospital, Juntendo university school of medicine
Outcome results
None listed