Platelet rich plasma transplantation for the intentional tooth replantation

Exploratory clinical study to evaluate the safety of Platelet rich plasma transplantation in the intentional tooth replantation - Platelet rich plasma transplantation for the intentional tooth replantation

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTc030190275

Enrollment

Registered

2020-03-31

Start date

2019-03-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of dental root

Interventions

administration of cell processing products.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Have a fracture of dental root. 2) Have a tooth which considered to effective by the tooth replantation. 3) Have good systemic condition. 4) Number of platelet is over 1x10E5 /microliter. 5) 20 years and older. 6) Other,the investigator believes makes him/her suitable for participation in this clinical study.

Exclusion criteria

Exclusion criteria: 1) Have a separated dental root and have an abscess at the root apical. 2) Have a history of Complicate malignant tumor. 3) Have an abnormal gingival proliferation or having a history of abnormal gingival proliferation. 4) Suspected of oral malignant tumor or precancerous lesion. 5) Under 20 years of old. 6) Have anti-coagulant or anti-platelet medications, or have a bleeding disorders. 7) Pregnancy, breastfeeding, or possibility of pregnancy 8) Other,the investigator believes makes him/her unsuitable for participation in the clinical study.

Design outcomes

Primary

Measure	Time frame
Safety	—

Secondary

Measure	Time frame
Efficacy	—

Countries

Japan

Contacts

Public ContactYosuke Masubuchi

Juntendo university

y-masubuchi@juntendo.ac.jp+81-3-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026