Health probrem studied
Conditions
Interventions
Root resection will be performed in accordance with the back root canal filling method using MTA cement supervised by the Japan Endodontic Society. CGF is prepared by centrifugation, and divided into
Sponsors
Saito Masahiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Root resection is considered an effective means for resolving the patient's chief complaint and hopes 2. Patients with good general condition 3. Patients with a platelet count of 100,000 / mm3 or more 4. Patients aged 20 to 70 5. Consent for participation in research should be obtained in writing
Exclusion criteria
Exclusion criteria: 1. Patients who have or have a history of malignancy 2. Patients with abnormal gingival growth or history 3. Malignant tumors, precancerous lesions or suspicious findings are observed in the oral cavity diagnosis 4. Patients under 20 or over 70 5. Other patients who are judged inappropriate by dentists who provide regenerative medicine etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Statistical analysis items Preoperative dental cone beam CT and intraoperative bone defect classification Observation of three-dimensional bone regeneration by dental cone beam CT imaging at 6 months after surgery Measurement of lesion reduction rate Take dental photographs every 3 months up to 12 months and measure the reduction rate of lesions The above data will be used to compare the effectiveness of bone regeneration between the two groups with and without CGF using statistical methods such as Mann-Whitney's U test or Student t-test. 2) Determination of clinical symptoms Immediately before and after surgery, determine the degree of pain, percussion pain, and apical tenderness during the follow-up period | — |
Countries
Japan
Contacts
Public ContactYoshio Yahata
Tohoku University Graduate School of Dentistry
Outcome results
None listed