Axial spondyloarthritis
Conditions
Sponsors
Eli Lilly Japan K.K.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: -Are ambulatory. -Diagnosis of radiographic axial spondyloarthritis (rad-xSpA) with sacroiliitis defined radiographically according to the modified New York criteria. -Participants have a history of back pain >= 3 months with age at onset <45 years. -In the past had an inadequate response to at least 1 non-steroidal anti-inflammatory drug (for duration 12 weeks) or cannot tolerate NSAIDS. -If taking NSAIDS be on a stable dose for at least 2 weeks prior to randomization. -Have a history of prior therapy for axSpa for at least 12 weeks prior to screening. Exclusion Criteria: -Have total ankylosis of the spine. -Have received any prior, or are currently receiving, treatment with biologics, tumor necrosis factor inhibitors or other immunomodulatory agents. -Have recently received a live vaccine within 12 weeks or have had a vaccination with Bacillus Calmette-Guerin (BCG) within the past year. -Have an ongoing or serious infection within the last 12 weeks or evidence of active tuberculosis. -Have a compromised immune system. -Have any other serious and/or uncontrolled diseases. -Have either a current diagnosis or a recent history of malignant disease. -Have had major surgery within 8 weeks of baseline, or will require surgery during the study. -Are pregnant or breastfeeding.
Exclusion criteria
Exclusion criteria:
Outcome results
None listed