Open-label trial to evaluate dopamine transporter occupancy in the human brain following repeated oral administration of OPC-64005 in healthy adult male subjects

Status

Unknown

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT2080222882

Enrollment

Registered

2015-06-11

Start date

2015-06-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

investigational material(s) Generic name etc : OPC-64005 INN of investigational material : Therapeutic category code : 117 Psychotropic agents Dosage and Administration for Investigational material :

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy adult male subjects

Exclusion criteria

Exclusion criteria: - History of drug or alcohol abuse within 2 years prior to screening. - History of or current hepatitis or acquired immunodeficiency syndrome. - History of drug allergy.

Design outcomes

Primary

Measure	Time frame
Dopamine transporter occupancy.	—

Secondary

Measure	Time frame
Plasma concentration, Safety	—

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026