A study assessing IOP fluctuations of K-115 in combination with latanoprost

A study assessing intraocular pressure (IOP) fluctuations of K-115 in combination with latanoprost: a clinical pharmacological study in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH)

Status

Unknown

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT2080222237

Enrollment

Registered

2013-09-30

Start date

2013-09-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POAG or OH

Interventions

investigational material(s) Generic name etc : K-115 INN of investigational material : Therapeutic category code : 131 Agents for ophthalmic use Dosage and Administration for Investigational material

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with POAG or OH 2. IOP after a run-in period with latanoprost>=18mmHg

Exclusion criteria

Exclusion criteria: 1.Patients with decreased visual performance 2.Patients thought to use glaucoma medication during this trial 3.Patients thought to wear contact lenses during this trial etc.

Design outcomes

Primary

Measure	Time frame
Efficacy :IOP Safety :Adverse event (AE) and adverse drug reaction (ADR) Efficacy : Change in IOP from baseline in the study eye at week 4 and 8 Safety : AE and ADR	—

Secondary

Measure	Time frame
Efficacy : IOP Efficacy : Change in IOP from baseline in both eyes at week 4 and 8	—

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026