Parkinson's disease
Conditions
Sponsors
ONO PHARMACEUTICAL CO.,LTD.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy adult part 1. : BMI >=18.5, <25.0 Age : 20 to 45 years Sex : male Parkinson's disease patient part 1. Patients who have been diagnosed with Parkinson's Disease according to the clinical diagnosis criteria of UK Parkinson's Disease Society Brain Bank 2. Patients who have been administered levodopa/carbidopa hydrate combination tablets without prescription change within 28 days in prior to the study drug administration in the Period 1 Age : 20 to 74 years Sex : male and female
Exclusion criteria
Exclusion criteria: Healthy adult part 1. A volunteer who has developed acute gastrointestinal symptoms (e.g. diarrhea, nausea, heart burn) within 7 days in prior to the study drug administration, or a volunteer who is observed with these gastrointestinal symptoms on a daily basis. Parkinson's disease patient part 1. A patient whose medical history, physical findings, laboratory test results can suggest parkinsonism from other causes than Parkinson's Disease 2. A patient who has received surgical treatments for Parkinson's Disease such as stereotactic neurosurgery, or who is planned with surgical treatments during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety, PK | — |
Outcome results
None listed