Solid Tumors, Lymphoma
Conditions
Interventions
investigational material(s)
Generic name etc : LY2875358
INN of investigational material :
Therapeutic category code : 429 Other antitumor agents
Dosage and Administration for Investigational materi
Sponsors
Eli Lilly Japan K.K.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Part A Have histological or cytological evidence of malignancies (solid tumor or lymphoma) that are advanced and/or metastatic. The participant must be, in the judgment of the investigator, an appropriate candidate for experimental therapy after available standard therapies have been used. Part B1 Have histological or cytological diagnosis of advanced NSCLC, stage IV. Patients must be eligible for erlotinib therapy. Part B2 Have histological or cytological diagnosis of advanced NSCLC, stage IV. Patients must be eligible for gefinitib therapy. - Have adequate hematologic, hepatic and renal function. - Have a performance status of equal to or less than 2. - Have discontinued all previous cancer therapies, and any agents that have not received regulatory approval for any indication, for at least 21 days or 5 half lives prior to study enrollment, whichever is shorter, and recovered from the acute effects of therapy - Have an estimated life expectancy, that will permit the participant to complete 8 weeks of treatment.
Exclusion criteria
Exclusion criteria:
Outcome results
None listed