Phase 3 clinical study of RM-003 in patients with homocystinuria

Status

Unknown

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT2080221773

Enrollment

Registered

2012-04-20

Start date

2012-04-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Homocystinuria, described as the following cases

Interventions

investigational material(s) Generic name etc : RM-003 INN of investigational material : Therapeutic category code : 399 Agents affecting metabolism, n.e.c. Dosage and Administration for Investigation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Homocystinuria, described as the following cases - cystathionine beta-synthase deficiency(CBS) - 5,10-methylenetetrahydrofolate reductase deficiency - defects in cobalamin metabolism

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Plasma total homocysteine levels at the end of the treatment	—

Secondary

Measure	Time frame
Plasma total homocysteine levels at each visit of the treatment Plasma homocystine levels at the end of the treatment	—

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026