Exploratory study of OPC-12759 Ophthalmic Suspension

Exploratory study of OPC-12759 Ophthalmic Suspension for patients with keratoconjunctival epithelial disorder

Status

Unknown

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT2080221666

Enrollment

100

Registered

2011-12-05

Start date

2011-12-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconjunctival epithelial disorder

Interventions

investigational material(s) Generic name etc : OPC-12759 ophthalmic suspension INN of investigational material : Therapeutic category code : 131 Agents for ophthalmic use Dosage and Administration fo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Diagnosis of superficial punctate keratopathy or corneal erosion 2. Fluorescein corneal staining score of 3 or higher

Exclusion criteria

Exclusion criteria: 1. Active ocular infection 2. Vernal keratoconjunctivitis 3. Recurrent corneal erosion 4. Physical irritation of eyelashes or relaxed bulbar conjunctiva to cornea or conjunctiva 5. Subjects who cannot discontinue or anticipate use of eye drops except for limited concomitant ones during the study. Soft-santear is allowed during the screening period. 6. Anticipated use of contact lens during the study. 7. Insertion of punctal plug or fall out of punctal plug within 3 months 8. Subjects who are judged by the investigator to be ineligible for the study because of a past or concurrent systemic disease. 9. Receipt of any investigational product within 4 months

Design outcomes

Primary

Measure	Time frame
Change in keratoconjunctival staining scores	—

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026