Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Adults 18 years of age or more - BMI of (a) 30 kg/m2 or more, or (b) 27kg/m2 or more and have a current diagnosis of at least 1 weight-related comorbidities (treated or untreated) - A stable body weight for 3 months prior to Screening (+-5% body weight change)
Exclusion criteria
Exclusion criteria: - Have obesity induced by other endocrine disorders, such as Cushing's syndrome or Prader-Willi syndrome - Has received prescription or non-prescription medication for weight loss within the last 3 months prior to Screening - Previous or planned (within study period) bariatric surgery or fitting of a weight loss device (eg, gastric balloon or duodenal barrier) - History of type 1 diabetes mellitus or T2DM
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Percent change in body weight from baseline to week 26 - Weight loss 5% or more from baseline weight to week 26 | — |
Countries
Australia, Canada, Japan, Poland, United Kingdom, US
Contacts
Astrazeneka K.K