Immediate Effect of Transcutaneous electrical nerve stimulation on pain and physical performance outcomes in patients with osteoarthritis of the knee: study protocol of a randomized controlled trial

Immediate Effect of Transcutaneous electrical nerve stimulation on pain and physical performance outcomes in patients with osteoarthritis of the knee: study protocol of a randomized controlled trial - Transcutaneous electrical nerve stimulation and knee OA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1092220322

Enrollment

Registered

2018-01-15

Start date

2018-01-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Intervention type:DEVICE Name of intervention:Transcutaneous electrical nerve stimulation Dose form / Japanese Medical Device Nomenclature:DEVICE Transcutaneous electrical nerve stimulation device Rou

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: to be over 50 years old. to have knees with Kellgren-Lawrence (K/L) grades 1-3 in one or both knees as evaluated using weight-bearing anteroposterior radiographs. to experience current average pain of more than 4 and less than 9 on a Numeric Rating Score (NRS; 0-10 points)

Exclusion criteria

Exclusion criteria: (1) have a history of knee surgery or intra-articular corticosteroid or hyaluronic acid injection within 6 months19, (2) have a history of knee joint replacement or tibial osteotomy, (3) are receiving physical therapy, (4) have any other major joint pain (e.g. back, hip or ankle) which gives a greater effect than their knee pain for current limits of the ability, (5) are in case of contraindications of TENS (pacemakers, dermatological conditions, and abnormal sensation in the knees) , (6) are severe medical or nervous conditions, (7) do not usually use stairs, (8) do not have ability to walk without any ambulatory assistive device

Design outcomes

Primary

Measure	Time frame
performance of functional tests, knee pain	—

Secondary

Measure	Time frame
locomotive syndrome risk test	—

Countries

Japan

Contacts

Public ContactKanako Shimoura

Graduate School of Medicine, Kyoto University

shimoura.kanako.53s@st.kyoto-u.ac.jp+81-75-751-3952

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026