Dementia treatment with combination of hydrogen gas and reduced dose lithium.

A combined treatment for Alzheimer's dementia with hydrogen gas inhalation and reduced dose lithium. A randomized controlled clinical study. - H2LiTxDementia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1091220303

Enrollment

Registered

2017-07-18

Start date

2017-02-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's dementia

Interventions

Intervention type:DRUG Name of intervention:H2 gas inhalation Dose form / Japanese Medical Device Nomenclature:INHALANT Route of administration / Site of application:ORAL,INHALATIONAL Dose per adminis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Alzheimer's dementia patient with confirmed worsening of clinical symptoms, MMSE score and ADAS score.

Exclusion criteria

Exclusion criteria: Dementia patient affected by other type of dementia rather than Alzheimer type, severe functional abnormality in the kidney, liver, pancreas and uncontrolled diabetes, lipidemia and hypertension.

Design outcomes

Primary

Measure	Time frame
Neurological improvement and improvements in MRI indices	—

Countries

Japan

Contacts

Public ContactHirohisa Ono

Nishijima Hospital

hirohisa.ono@live.jp+81-55-922-8235

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026