Evaluation of oral hyaluronan effect for skin wrinkle

Evaluation of oral hyaluronan effect (molecular weights 2k and 300 k) for skin wrinkle: a randomized, double blind, controlled study over a 12 weeks period. - HA trial to skin

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1091220234

Enrollment

Registered

2015-12-18

Start date

2015-01-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

skin wrinkle

Interventions

Intervention type:DRUG Name of intervention:hyaluronan Dose form / Japanese Medical Device Nomenclature:CAPSULE Route of administration / Site of application:ORAL Dose per administration:120 mg Dosing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individual with wrinkle at the corners of eyes

Exclusion criteria

Exclusion criteria: 1.Currently taking oral or topical medication which may affect the test result. 2.Pregnant, possibly pregnant, or lactating. 3.Currently taking excessive alcohol. 4.Likely to have a skin allergy (with symptoms of atopic dermatitis). 5.Likely to be acutely allergic to the test material. 6.Participating in another clinical test. 7.Continuously taking hyaluronan as a medicine or a dietary supplement. 8.Usual symptoms of diarrhea or stomach ache.

Design outcomes

Primary

Measure	Time frame
Skin wrinkle	—

Secondary

Measure	Time frame
Subjective opinion on the skin condition	—

Countries

Japan

Contacts

Public ContactOe Mariko

Kewpie corporation

mariko_oe@kewpie.co.jp+81-3-5384-7759

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026