The effects of alpha-lipoic acid supplementation on muscle atrophy after anterior cruciate ligament reconstruction.

The effects of alpha-lipoic acid supplementation on muscle atrophy after anterior cruciate ligament reconstruction: a randomized controlled trial - The effects of antioxidant supplementation on muscle atrophy after ACL reconstruction.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1091220219

Enrollment

Registered

2015-07-24

Start date

2015-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anterior cruciate ligament reconstruction

Interventions

Intervention type:DRUG Name of intervention:alpha-lipoic acid Dose form / Japanese Medical Device Nomenclature:CAPSULE Route of administration / Site of application:ORAL Dose per administration:105 21

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients diagnosed as anterior cruciate ligament injury.

Exclusion criteria

Exclusion criteria: Subjects were excluded if they were currently using antioxidant supplements.

Design outcomes

Primary

Measure	Time frame
muscle volume	—

Secondary

Measure	Time frame
oxidative stress markers, inflammation markers	—

Countries

Japan

Contacts

Public ContactDaisuke Ando

University of Yamanashi

dandoh@yamanashi.ac.jp+81-55-220-8208

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026