Patients who scored more than 8 on F scale questionnaire after taking NSAIDs more than 4 weeks are enrolled.
Conditions
Interventions
Intervention type:DRUG
Name of intervention:Oral administration esomeprazole on symptoms indicative of gastroesophageal reflux disease observed in patients taking non-steroidal anti-inflammatory drug
Sponsors
Department of Orthopedic surgery, graduate school of medicine, Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who scored more than 8 on F scale questionnaire after taking NSAIDs more than 4 weeks are enrolled.
Exclusion criteria
Exclusion criteria: 1 Those who have bleedings from gastrointestinal system, sudden decrease of body weight 2 Those who have organic brain damage, schizophrenia 3 Alcohol dependency, drug abuse 4 Hormonal disorders such as hyperthyroidism 5 Severe renal or liver dysfunction, hematopoietic disorders 6 Those who take more than two anti-coagulants 7 Those who are allergic to drugs to be tested 8 Those who are pregnant or who wish to be pregnant during corresponding clinical test 9 Patients who are not regarded as improper by physician in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FSSG scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Subscores of FSSG scale | — |
Countries
Japan
Contacts
Public ContactSasho, Takahisa
Graduate school of medicine, Chiba University
Outcome results
None listed