post-stroke hemiparesis
Conditions
Interventions
Intervention type:DRUG
Name of intervention:Effects of rTMS therapy in assessing stroke hemiparesis
Dose form / Japanese Medical Device Nomenclature:DEVICE
Route of administration / Site of applicatio
Sponsors
The Jikei University School of Medicine
The Jikei University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) motor-dominant aphasia caused by left hemispheric stroke in a right-handed subject; 2) age at intervention between 20-80 years; 3) time between the onset of stroke and treatment of more than 12 months; 4) history of a single stroke only (no bilateral cerebrovascular lesion); 5) no cognitive impairment with a pretreatment Mini Mental State Examination score of more than 26; 6) clinical confirmation of a plateau state (no increases in the WAB and Token Test scores as measured by a speech therapist from the institution in the last 3 months); 7) no active physical or mental illness requiring medical management; 8) no contraindications to atomoxetine administration (serious cardiovascular disturbance, pheochromocytoma, closed angle glaucoma and impaired liver function); and 9) sufficient understanding of the study contents.
Exclusion criteria
Exclusion criteria: contraindications to atomoxetine administration (serious cardiovascular disturbance, pheochromocytoma, closed angle glaucoma and impaired liver function)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safety, feasibility, and efficacy | — |
Secondary
| Measure | Time frame |
|---|---|
| Japanese version of WAB and the Token Test | — |
Countries
Japan
Contacts
Public ContactNaoki Yamada
The Jikei University School of Medicine
Outcome results
None listed