Comparison of analgesic effect between celecoxib and loxoprofen after orthopedic surgery

Comparison of analgesic effect between celecoxib and loxoprofen after orthopedic surgery - Comparison of analgesic effect between celecoxib and loxoprofen after orthopedic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1091220149

Enrollment

Registered

2013-11-22

Start date

2013-11-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing orthopedic procedures and being given general anesthesia, but not undergoing epidural anesthesia, iv-PCA, or nerve block anesthesia

Interventions

Intervention type:DRUG Name of intervention:Celecoxib group Dose form / Japanese Medical Device Nomenclature:TABLET Route of administration / Site of application:ORAL Dose per administration: Celecoxi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing orthopedic procedures and being given general anesthesia Patients able to understand this study, and able to agree by themselves

Exclusion criteria

Exclusion criteria: Patients undergoing epidural anesthesia, iv-PCA, or nerve block anesthesia Patients who have peptic ulcer, renal dysfunction(serum creatinine: male>1.5 female>1.2), who has been angina, cardiac infarction, or heart failure. Patients who cannot understand VAS score

Design outcomes

Primary

Measure	Time frame
Compare VAS score between celecoxib and loxoprofen group 2 hours after surgery, 4 hours after surgery, and 1hour after the next day's breakfast	—

Secondary

Measure	Time frame
Compare rescue dose of analgesics, and side effects between celecoxib group and loxoprofen group	—

Countries

Japan

Contacts

Public ContactMasanao Okabayashi

Sekitetsukai Tanabe Chuou Hospital

okaba0402@msn.com+81-774-63-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026