Persistent atrial fibrillation
Conditions
Interventions
Intervention type:DRUG
Name of intervention:Bepridil hydrochloride
Dose form / Japanese Medical Device Nomenclature:
Route of administration / Site of application:
Dose per administration:
Dosing freq
Sponsors
Bepridil central office
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Persistent AF lasting 7 days or longer by electrocardiogram in term of the surveillance
Exclusion criteria
Exclusion criteria: 1)Persistent AF lasting 1 year or longer. 2)Cardiac surgery, myocardial infarction within 1 month of the onset or unstable clinical manifestation. 3)AF because of underlying disease or complications as follows; sick sinus syndrome, giant left atrium, AF with disturbances of conduction, hyperthyrea, mitral stenosis. 4)left ventricular ejection fraction <= 40%, or heart failure level III orIV at New York Heart Association classification of cardiac performance. 5)Bradyasystolic AF. 6)marked QT increased. 7)a history of syncope because of polymorphic ventricular tachycardia or antiarrhythmic agent. 8)very low blood pressure 9)Contraindication for anticoagulation therapy 10)Severe liver and/or kidney dysfunction 11)a history of Bepridil 12)a history of administrated other CTM 13)females of known or suspected pregnancy 14)Patients disqualified participating this trial by Dr.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of patients recognized sinus rhythm by electrocardiographic representation throughout clinical study | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to sinus rhythm, improvement rate of subjective symptom | — |
Countries
Japan
Outcome results
None listed