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Comprehensive analysis of genetic predisposition in refractory asthma

Comprehensive analysis of genetic predisposition in refractory asthma - Analysis of genetic predisposition in refractory asthma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1090220341
Enrollment
20
Registered
2018-04-05
Start date
2017-11-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory asthma

Interventions

Intervention type:PROCEDURE Name of intervention:Biopsy and Blood sampling Dose form / Japanese Medical Device Nomenclature:DEVICE Bronchial thermoplasty Route of administration / Site of application:

Sponsors

None listed

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who are diagnosed with bronchial asthma and require high-dose inhaled corticosteroids and long-acting beta2 stimulants for asthma control. 2.Other patients applicable to the proper usage criteria of bronchial thermoplasty system.

Exclusion criteria

Exclusion criteria: 1.Patients who are later found out to have a disease other than bronchial asthma. 2.Patients who other researchers judged inappropriate.

Design outcomes

Primary

MeasureTime frame
Variable genes in the airway tissues or mononuclear cells in the peripheral blood of severe asthma patients

Secondary

MeasureTime frame
Pathological images of airway tissues before and after bronchial thermoplasty

Countries

Japan

Contacts

Public ContactSatoshi Ano

National Hospital Organization Kasumigaura Medical Center

ano.satoshi.ab@mail.hosp.go.jp+81-29-822-5050

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026