Trial to confirm biological activities in humans after long term intake of polyamine-rich food -interventional tial using newly developed fermented soybeans "Natto"-

Trial to confirm biological activities in humans after long term intake of polyamine-rich food -interventional tial using newly developed fermented soybeans "Natto"- - Biological activities leading to healthy long life by high polyamine diet

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1090220233

Enrollment

Registered

2015-12-18

Start date

2015-12-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inhibition of aging-associated diseases

Interventions

Intervention type:BEHAVIOUR Name of intervention:Continuous intake of Natto, fermented soy bean products Dose form / Japanese Medical Device Nomenclature:NOT APPLICABLE Route of administration / Site

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy volunteer

Exclusion criteria

Exclusion criteria: soybean allergy, cancer patients

Design outcomes

Primary

Measure	Time frame
Changes in blood polyamine levels. Changes of blood data induced by polyamine, sucha as LFA-1(lymphocyte function associated antigen 1) expression on immune cells, blastoid transformation of lymphocyte by con-A, HDL, LDL, and CRP.	—

Secondary

Measure	Time frame
event of aging-associated diseases	—

Countries

Japan

Contacts

Public ContactKuniyasu Soda

Saitama Medical Center, Jichi Medical University

soda@jichi.ac.jp+81-48-647-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026