Kamisyoyosan's effects on some menopausal symptoms study:KOSMOS Study

The exploratory study of the efficacy and the safety of Kamishoyosan on menopausal symptoms

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1080223160

Enrollment

Registered

2016-04-04

Start date

2016-04-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopausal disorders

Interventions

investigational material(s) Generic name etc : TJ-24 (TSUMURA Kamishoyosan Extract Granules) INN of investigational material : - Therapeutic category code : 52- Chinese medicines Dosage and Administra

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Menopausal disorder patients 2) Patients who had mental manifestation. 3) Patients who had vasomotor sympotms. 4) Agreement to sign an informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with an extremely weak gastrointestinal tract 2) Patients with anorexia, nausea and vomiting 3) Patients with severe psychiatric disorder 4) Patinets with serious complications 5) Patients who are decided inadequate by their doctor

Design outcomes

Primary

Measure	Time frame
safety efficacy The change in menopansal symptom (excitement and irritability)	—

Secondary

Measure	Time frame
safety efficacy The change in menopansal symptom (except excitement and irritability) The change in QOL	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026