dysphagia,gastroesophageal reflux disease,laryngopharyngeal reflux dysphagia,gastroesophageal reflux disease,laryngopharyngeal reflux
Conditions
Interventions
Swallowing function testing with laryngeal fiber and impedance-pH testing are routinely performed in patients with suspected severe dysphagia.
Highresolution esophageal manometry is performed to ass
Sponsors
Masui Daisuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: In particular, Neurologically impaired patients who suspected dysphagia will be recruited by explaining the study in writing to patients admitted to pediatric surgery department of Kurume University Hospital, and patients who have given their consent will be included. Patients who have obtained written consent to participate in the study from their surrogate.
Exclusion criteria
Exclusion criteria: Children with organic stenosis in the oesophagus who have difficulty inserting an impedance catheter or high-resolution oesophageal manometric catheter. Those deemed unsuitable as research subjects by the principal investigator and research assistants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the usefulness of salivary pepsin and alpha amylase concentrations as an assessment of dysphagia in Neurologically Impaired Patients. the usefulness of measuring pepsin and alpha amylase concentrations in airway secretions as an assessment of dysphagia in Neurologically Impaired Patients. the relationship between pH impedance testing and pharyngeal pressure in high-resolution intra-oesophageal pressure testing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Classification of the type of dysphagia or swallowing pneumonia based on the results of swallowing endoscopy and pH impedance testing and high-resolution intra-oesophageal pressure testing. | — |
Contacts
Public ContactDaisuke Masui
Kurume University School of Medicine
Outcome results
None listed