Multi-institutional retrospective observational study of definitive radiotherapy/chemoradiotherapy in cervical cancer

Multi-institutional retrospective observational study of definitive radiotherapy/chemoradiotherapy consisting of external beam radiotherapy without central shielding and 3-dimensional image-guided brachytherapy in cervical cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1072210070

Enrollment

150

Registered

2021-09-30

Start date

2021-09-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine cervical cancer

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: For inclusion in the study, patient should fulfill the following criteria: 1.Pathologically diagnosed intact uterine cervical cancer 2.FIGO 2018 stages of IB1-3, IIA1-2, IIB, IIIA, IIIB, IIIC1-2, IVA 3.ECOG performance status of 0-3 4.Aged at 18 to 85 years 5.Diagnosis of squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma 6.Undergone definitive radiotherapy/chemoradiotherapy consisting of external beam radiotherapy (3DCRT/IMRT) without central shielding and 3D-image guided brachytherapy between January 2014 and June 2020 7.No prior chemotherapy (NAC) or surgery for cervical cancer 8.No history of surgery for other pelvic malignancies

Exclusion criteria

Exclusion criteria: Patients should not enter the study if any of the following exclusion criteria are fulfilled: 1.History of another malignancy within 5 years 2.Inadequate medical information 3.Refusal from patients or representatives

Design outcomes

Primary

Measure	Time frame
2-year local progression-free survival	—

Secondary

Measure	Time frame
2-year distant metastases-free survival, 2-year progression-free survival, 2-year overall survival, 2-year incidence of late complications (rectum, bladder, sigmoid colon, small bowel, others)	—

Contacts

Public ContactTakafumi Toita

Okinawa Chubu Hospital

toitattt@gmail.com+81-98-973-4111

Outcome results