Healthy volunteer stomach, gastric excretion rate
Conditions
Interventions
- Acetaminophen administration for gastric emptying rate assessment
- Local anesthesia and catheter insertion for gastric status assessment
Acetaminophen, local anesthetic, catheter
Sponsors
Yokota Shouji
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Healthy Japanese adult males aged 18 to 45 years at the time of consent Subjects weighing 50 to 80 kg Subjects with a BMI of 18.5 to 25.0 (rounded down to one decimal place)
Exclusion criteria
Exclusion criteria: Persons with a history of major gastrointestinal surgery, such as gastrectomy, gastrointestinal suture, or intestinal resection (appendectomy and inguinal hernia repair are acceptable). Persons with a history of serious illnesses, such as cerebrovascular disease, thromboembolism, ischemic heart disease, autoimmune disease, or convulsive disorders (including epilepsy). Persons with drug hypersensitivity or allergies. Alcohol or drug addicts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric emptying rate, gastric content evaluation (gastric pH, etc.), total gastric content volume evaluation, etc. | — |
Contacts
Public ContactTomohisa Kato
Sawai Pharmaceutical Co., Ltd.
Outcome results
None listed