Medication-related osteonecrosis of the jaw osteonecrosis of the jaw, bisphosphonate, denosumab
Conditions
Interventions
Patients who meet the registration requirements are aske d to take two nutritional supplements (whey peptide-cont aining liquid diet) a day for a total of 14 days, 7 days befor e surgery and 7 days af
nutrient, whey peptide-containing liquid diet
Sponsors
Hara Masahito
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 18 years or older at the time of informed consent Regardless of gender Performance Status From 0 to 2 Patients who have given written informed consent of their own free will after receiving sufficient explanation about participating in this study
Exclusion criteria
Exclusion criteria: Patients who have difficulty in taking nutritional supplements orally before surgery For example, patients with severe dementia or on parenteral nutrition Patients on dialysis Patients with diabetes (HbA1c of 6.5 or high) Obese patients (BMI of 25 or high) Patients with milk allergy or soy allergy Other patients who are judged by the attending physician to be inappropriate as research subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nutritional status 8 days after surgery (serum albumin, ser um total protein, prealbumin) | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence or absence of postoperative complications, changes in nutritional status 1 to 3 months after surgery (weight change rate, BMI, CONUT value) | — |
Contacts
Public ContactMasahito Hara
Nagasaki University Hospital
Outcome results
None listed