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The influence of remimazolam on the neuromuscular transmission

The influence of remimazolam on the neuromuscular transmission

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1071230039
Enrollment
15
Registered
2023-07-12
Start date
2023-07-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for elective surgery under general anesthesia in the supine position

Interventions

None listed

Sponsors

Fujimoto Masafumi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients over 18 years old scheduled for elective surgery under general anesthesia in the supine position without neuromuscular blockade. All patients were American Society of Anesthesiologists physical status class I or II.

Exclusion criteria

Exclusion criteria: Patients under 18 years old, with known or suspected difficult airway and a history of gastroesophageal reflux or increased risk factors for aspiration, with neuromuscular disorder, with contraindication to benzodiazepine

Design outcomes

Primary

MeasureTime frame
Changes of TOF ratio and T1 response after conversion of maintenance of anesthesia with propofol to that with remimazolam

Secondary

MeasureTime frame
Correlation between the rate of changes of TOF ratio or T1 response and basic demographic data of the patients (age, sex, height, weight, body mass index, liver and renal function), dose of remimazolam and depth of anesthesia

Countries

Japan, noe

Contacts

Public ContactMasafumi Fujimoto

Kumamoto University Hospital

mfujimoto.kmm@gmail.com+81-96-373-5275

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026