Efficacy of corticosteroid irrigation of the major salivary glands for xerostomia following head and neck cancer radiotherapy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1071210017

Enrollment

Registered

2021-04-30

Start date

2022-10-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia dry mouth, xerostomia, radiotherapy, head and neck cancer

Interventions

Irrigation group: Oral management and corticosteroid irrigation were carried out 4 times (treatment 1-4) with an interval of 7 (4-10) days. Control group: Oral management was carried out 4 times (tre

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: head and neck cancer patients receiving radiotherapy (IMRT) with dose greater than 50 Gy One or more parotid and submandibular glands are included in the field of radiation.

Exclusion criteria

Exclusion criteria: Patients with problem in judgement

Design outcomes

Primary

Measure	Time frame
xerostomia 4 weeks after treatment	—

Secondary

Measure	Time frame
xerostomia on treatment 1-4 xerostomia on 4, 8,12 weeks after treatment salivary flow rate on treatment 1-4 salivary flow rate 8,12 weeks after treatment	—

Contacts

Public ContactYukinori Takagi

Nagasaki University Hospital

yuki@nagasaki-u.ac.jp+81-95-819-7708

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026