A Study to Confirm the Extent of Hemolysis and Renal Impairment in Radiofrequency Ablation for Atrial Fibrillation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1070250078

Enrollment

Registered

2025-09-30

Start date

2025-08-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation Atrial fibrillation

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing initial radiofrequency catheter ablation for atrial fibrillation

Exclusion criteria

Exclusion criteria: Patients meeting any of the following criteria: Currently participating in another clinical trial or clinical research (interventional study) Left ventricular ejection fraction ==55 mm Renal impairment with serum creatinine >=1.5 mg/dL Post-valvular surgery (including catheter-based treatment) Post-Maze surgery Severe valvular disease Active malignant neoplasm

Design outcomes

Primary

Measure	Time frame
Degree of increase in free hemoglobin in T2, T3, and T4 Degree of increase in creatinine in T2, T3, and T4 Incidence of kidney injury stage1 or higher according to KDIGO clinical guidelines	—

Secondary

Measure	Time frame
Degree of elevation in total bilirubin and LDH during T2, T3, and T4 Degree of decrease in serum hemoglobin during T2, T3, and T4 Degree of elevation in BUN during T2, T3, and T4 Frequency of patients with haptoglobin levels falling below the detection limit on the day after surgery	—

Contacts

Public ContactHideharu Okamatsu

Saiseikai Kumamoto Hospital

hideharu-okamatsu@saiseikaikumamoto.jp+81-96-351-8000

Outcome results