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Brain MRI analysis for fibromyalgia patients

Quantitative analysis of brain functional and structural networks using MRI in patients with fibromyalgia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1070230082
Enrollment
26
Registered
2023-11-05
Start date
2023-10-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fibromyalgia Fibromyalgia, MRI

Interventions

Sponsors

Sasara Takeshi
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: (1) Fibromyalgia cases: Diagnosed with Fibromyalgia according to the American College of Rheumatology (ACR) Fibromyalgia criteria (Wolfe et al., 2010), age 18 or older, younger than 75, and right-handed female. (2) Healthy subjects: Those with no neuropsychiatric medical treatment or history, who scored in the healthy range on the Psychological Stress Response Scale (SRS-18), aged 18 to under 75, right-handed female.

Exclusion criteria

Exclusion criteria: If contraindications for MRI apply (cardiac pacemaker, cerebral artery clipping surgery, internally implanted devices, etc., pregnant women, etc.)

Design outcomes

Primary

MeasureTime frame
1)Brain volume: Cortical and subcortical brain volume values for each brain region (mm3), (Anterior cingulate gyrus, Insura cortex, Prefrontal cortes, Hippocampal and Amygdala volume measurement) 2)Quantitative measure of nerve fiber bundles Fractional Anisotrophy 3)Resting-state functional brain network (connection of emotion-related circuits (correlation coefficient between anterior cingulate gyrus and insular gyrus), connection of descending inhibitory system (anterior cingulate gyrus-central gray matter and ventromedial medulla oblongata) correlation coefficient between parts), default mode network map)

Secondary

MeasureTime frame
BPI, Brief Pain Inventory, Japanese version PCS, Pain Catastrophizing Scale, Japanese version PSEQ, Pain Self-Efficacy Questionnaire, Japanese version HADS, Hospital Anxiety and Depression Sale, Japanese version

Contacts

Public ContactSasara Takeshi

Yuuikai Tomishiro Central Hospital

tsasara@mac.com+81-98-851-0501

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026