Fibromyalgia Fibromyalgia, MRI
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Fibromyalgia cases: Diagnosed with Fibromyalgia according to the American College of Rheumatology (ACR) Fibromyalgia criteria (Wolfe et al., 2010), age 18 or older, younger than 75, and right-handed female. (2) Healthy subjects: Those with no neuropsychiatric medical treatment or history, who scored in the healthy range on the Psychological Stress Response Scale (SRS-18), aged 18 to under 75, right-handed female.
Exclusion criteria
Exclusion criteria: If contraindications for MRI apply (cardiac pacemaker, cerebral artery clipping surgery, internally implanted devices, etc., pregnant women, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Brain volume: Cortical and subcortical brain volume values for each brain region (mm3), (Anterior cingulate gyrus, Insura cortex, Prefrontal cortes, Hippocampal and Amygdala volume measurement) 2)Quantitative measure of nerve fiber bundles Fractional Anisotrophy 3)Resting-state functional brain network (connection of emotion-related circuits (correlation coefficient between anterior cingulate gyrus and insular gyrus), connection of descending inhibitory system (anterior cingulate gyrus-central gray matter and ventromedial medulla oblongata) correlation coefficient between parts), default mode network map) | — |
Secondary
| Measure | Time frame |
|---|---|
| BPI, Brief Pain Inventory, Japanese version PCS, Pain Catastrophizing Scale, Japanese version PSEQ, Pain Self-Efficacy Questionnaire, Japanese version HADS, Hospital Anxiety and Depression Sale, Japanese version | — |
Contacts
Yuuikai Tomishiro Central Hospital