Rectal Cancer Abdominoperineal resection (APR)
Conditions
Interventions
After abdominoperineal resection, the perineal wound is closed using a semi-closure technique. On postoperative day 1, a negative pressure wound therapy (NPWT) device is applied to the perineal wound.
Sponsors
Ohdan Hideki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients scheduled to undergo abdominoperineal resection (APR) for colorectal surgery. (2) Patients diagnosed with colorectal cancer histologically according to the "Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma (9th Edition)," who have received preoperative radiotherapy and are scheduled for Negative Pressure Wound Therapy (NPWT). (3)/(4) Patients aged 18 years or older who have provided written informed consent prior to study enrollment.
Exclusion criteria
Exclusion criteria: (1) Patients with contaminated perineal wounds accompanied by active infection. (2) Patients with known hypersensitivity to chemical substances (e.g., urethane, polyvinyl alcohol, acrylic adhesives). (3) Patients with comorbid psychiatric disorders that may interfere with the evaluation of the efficacy and safety of this study. (4) Other patients judged by the investigator or sub-investigator to be unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of perineal surgical site infection (SSI) within 30 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1,Overall incidence of surgical site infection (SSI) 2,Incidence of SSI by anatomical site (Superficial, Deep, Organ/Space) 3,Length of hospital stay 4,Postoperative complications (Clavien-Dindo classification) 5,Causative pathogens of surgical site infection 6,Incidence of skin disorders associated with negative pressure wound therapy (NPWT) | — |
Contacts
Public ContactManabu Shimomura
Hiroshima University Hospital
Outcome results
None listed