Esophageal cancer Esophageal Neoplasms
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with esophageal cancer cStage 1-4a (Union for International Cancer Control criteria) and undergoing preoperative chemotherapy Male and female patients aged 20 years or older and 80 years or younger at the time of consent. Two courses of three drugs (docetaxel, cisplatin, and fluorouracil) will be administered as neoadjuvant chemotherapy.
Exclusion criteria
Exclusion criteria: Diagnosed with dementia Needs assistance in walking or moving around. Patients undergoing treatment other than chemotherapy such as radiation therapy Patients who are judged to be inappropriate as research subjects by the principal investigator and research coordinators. Patients who are prohibited from exercise therapy by the attending physician due to complications such as serious cardiac or renal disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walking distance | — |
Secondary
| Measure | Time frame |
|---|---|
| Lower limb muscle strength Respiratory muscle strength Muscle mass Extracellular water ratio Ability to perform activities of daily living Quality of life Physical activity Malnutrition Adherence adverse events Post-operative indicators Postoperative complications | — |
Contacts
Okayama University Hospital