anterior cruciate ligament injury anterior cruciate ligament
Conditions
Interventions
Hyperbaric oxygen (HBO) therapy. For the HBO combination group, HBO will be started the day after ACL reconstruction. A total of 10 times in a row excluding Saturdays and Sundays. The HBO protocol sho
hyperbaric oxygen therapy
Sponsors
Enokida Makoto
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Men and women aged 14 to 45 at the time of consent, 2) Patients with traumatic anterior cruciate ligament injury (whether fresh or old), 3) Patients with consent from the substitute
Exclusion criteria
Exclusion criteria: 1)Patients with inflammatory disease 2) Patients with intra-articular fracture and osteochondral injury 3) Patients using bone metabolism regulators 4) Patients receiving hyperbaric oxygen therapy within 1 month prior to obtaining consent 5) Patients with compound ligament injury who require surgical treatment for ligament injuries other than the anterior cruciate ligament 6) Patients with a history of surgical treatment on the affected knee 7) Patients with physical or mental illness who cannot perform MRI examination 8) Chronic lung disease, chronic sinusitis, nasal polyps, upper respiratory tract inflammation and other sinus stenosis have been pointed out, pneumothorax history, other laryngological diseases, etc. 9) When it is judged that HBO continuation is not preferable due to the exacerbation of the underlying disease 10) Patients found to be pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of maturation of the anterior cruciate ligament by MRI | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantitative evaluation of peripheral blood bone marrow-derived cell., Physical findings (knee joint swelling, muscle atrophy, range of motion, anterior movement amount, half-month movement amount over time), knee function evaluation, patient-standing knee function evaluation., Safety (adverse events, side effects) | — |
Contacts
Public ContactMakoto Enokida
Tottori University
Outcome results
None listed