Relationship between sedative drugs and EEG

Effects of different sedative drugs used during general anesthesia on intraoperative EEG components

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1061230052

Enrollment

Registered

2023-08-23

Start date

2023-08-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia anesthesia

Interventions

Anesthesia is started with sevoflurane or propofol, and the sedation method is switched to the other during the surgery.

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are at least 18 years of age and scheduled to undergo scheduled surgery, with a scheduled surgery time of at least 5 hours.

Exclusion criteria

Exclusion criteria: Patients with an American Society of Anesthesiologists physical status (ASA-PS) score of 3 or higher Emergency surgery Patients with preoperative cognitive dysfunction Patients taking antipsychotic medications Patients with drug or alcohol dependence Patients with a history of cerebral infarction, cerebral hemorrhage, or neurosurgery Patients who cannot have an EEG monitor placed on the forehead due to trauma or skin disorders

Design outcomes

Primary

Measure	Time frame
Differences in Alpha wave power in intraoperative EEG with propofol and sevoflurane	—

Contacts

Public ContactHideki Iwata

Department of Anesthesiology and Intensive Care Medicine

billy_blind2@yahoo.co.jp+81-88-880-2471

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026