Functional Dyspepsia Functional Dyspepsia
Conditions
Interventions
PPI (esomeprazole 10mg/day) monotherapy group
Starting from the date of diagnosis, esomeprazole 10 mg/day will be administered once daily for 56 days as a single agent.
No other supportive care such a
Sponsors
Yachida Tatsuo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All of the following are required 1) At least one symptom of dyspepsia on the mFSSG questionnaire 2) Helicobacter pylori (HP) negative or after HP eradication 3) 20 years of age or older 4) Patients must have one of the following symptoms: postprandial complaint syndrome (lethargy and early satiety after eating) or epigastric pain syndrome (epigastric pain and burning sensation in the epigastrium).
Exclusion criteria
Exclusion criteria: Persons who fall into any of the following categories are excluded 1) Patients with current HP infection 2) Patients with organic disease on upper gastrointestinal endoscopy 3) Patients who have already started medical treatment for the same symptoms 4) Patients taking NSAIDs (non-steroidal anti-inflammatory drugs) 5) Patients with a history of allergy to the drugs to be used 6) Patients deemed inappropriate by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scoring by mFSSG, GSRS, and VRS before and 2 weeks after treatment to examine improvement of symptoms in the early stages. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Scoring by mFSSG, GSRS, and VRST at 4 and 8 weeks to examine improvement of symptoms over time. (2) Presence or absence of adverse events of the drug | — |
Contacts
Public ContactTatsuo Yachida
Kagawa University Hospital
Outcome results
None listed