cervical cancer cervical cancer/ radiotherapy/ pelvic fracture
Conditions
Interventions
DEXA will be performed before and after radiotherapy and during the follow-up period to check for osteoporosis.
The osteoporosis group will receive osteoporosis drugs including selective estrogen rece
selective estrogen receptor modulator / osteoporosis
Sponsors
Nagao Shoji
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria will be considered. Patients with histologically confirmed cervical cancer. Patients who are scheduled to receive radical radiotherapy, including concomitant intracavitary irradiation, as initial treatment for cervical cancer. Postmenopausal patients ,menstrual amenorrhea for at least twelve months prior to the start of radiotherapy. Patients who have given written consent to participate in the study.
Exclusion criteria
Exclusion criteria: Patients who are expected to have difficulty completing the study or subsequent follow-up, or who are deemed unsuitable by their physicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| New pelvic fractures within the irradiation field 2 years after completion of radiotherapy *Fractures within the irradiation field are defined as fractures of the ilium, pubis, sit bones, sacrum, and fifth lumbar vertebrae. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) New fragility fractures of the whole body 2 years after completion of radiotherapy (2) Changes in pain scale (3) Changes in bone density, bone resorption markers, and bone matrix-related markers (4) Progression-free survival (5) Overall survival | — |
Contacts
Public ContactShinsuke Shirakawa
Okayama univercity
Outcome results
None listed