chronic functional constipation constipation
Conditions
Interventions
None listed
Sponsors
Kozuka Kazuhiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The following criteria will be considered for those who meet all of the following criteria 1Meet Rome IV criteria for chronic functional constipation 2No organic disease as a cause of constipation 3The patient is judged by our outpatient constipation clinic to require Elobixibat tablets as treatment for withdrawal from stimulant laxatives. 4Defecation is obtained by using stimulant laxatives. 5Not taking P-glycoprotein products 6Questionnaire items are audible.
Exclusion criteria
Exclusion criteria: Diseases such as intestinal obstruction or enteritis that may be aggravated by continued use of Elobixibat tablets during the follow-up period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of withdrawal from regular use of stimulant laxatives | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in (complete) spontaneous defecation frequency, Bristol Stool Form Scale, VAS score (pain, fullness, heaviness, abdominal discomfort), constipation score (CSS), JPAC-QOL score, need for concomitant use of other drugs, type and ratio of concomitant drugs, score comparison for each concomitant drug, adverse events Correlation between stool and gas retention position on abdominal x-ray and response cases, median time from oral administration to first bowel movement | — |
Contacts
Public ContactKazuhiro Kozuka
Department of Gastroenterology and Neurology
Outcome results
None listed