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Preperation intervention study for colonoscopy

A randomized controlled trial investigating whether taking precolonoscopic Movicol in patients with chronic constipation can reduce the dose of bowel lavage liquid

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1061210085
Enrollment
180
Registered
2022-03-18
Start date
2022-07-28
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic constipation

Interventions

As a preparation for colonoscopy, in addition to taking Picosulfate sodium solution the day before the exam, take Magmit tablets or Movicol for 3 days.

Sponsors

Kinugasa Hideaki
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients planning a colonoscopy 2. Patients with chronic constipation: Two or more of the following six criteria a)-f) are met and the patient has been symptomatic for at least 6 months and has met the criteria for the last 3 months: a) Straining during more than 1/4 (25%) of defecations. b) Lumpy or hard stools more than 1/4 (25%) of defecations. c) Sensation of incomplete evacuation more than 1/4 (25%) of defecations. d) Sensation of anorectal obstruction/blockage more than 1/4 (25%) of defecations. e) Manual maneuvers to facilitate more than 1/4 (25%) of defecations (e.g., digital evacuation, support of the pelvic floor). f) Fewer than three spontaneous bowel movement per week. 3. Patients who received sufficient explanation before participating in this study, and obtained written consent by the patient's free will after sufficient understanding. 4. Patients over 20 years old who can decide to participate in the study by themselves at the time of obtaining consent

Exclusion criteria

Exclusion criteria: 1. Already in the treatment of chronic constipation and regularly using Magmit tablets more than 1500 mg per day or Movicol more than 13.7046 g per day 2. Poor general condition 3. Emergency endoscope 4. Persistent bloody stool or endoscopy was for hemostasis 5. Patients with chronic kidney disease 6. Patients who plan to perform colonoscopy without intestinal lavage 7. Patients who cannot decide to participate in the exam by themselves 8. Patients who understand the exam well but do not agree to participate in the exam 9. Those who are judged to be inappropriate as research subjects by the principal investigator and the research coordinator

Design outcomes

Primary

MeasureTime frame
The amount of Moviprep drunk for intestinal lavage

Secondary

MeasureTime frame
1) Time to complete intestinal lavage 2) Degree of intestinal lavage 3) Tolerability 4) Safety

Contacts

Public ContactHideaki Kinugasa

Okayama University Hospital

hkinugasa14@okayama-u.ac.jp+81-86-235-7219

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026