Adult patients with cardiac arrest with persistent coma after ROSC and require intensive care adult cardiac arrest
Conditions
Interventions
Head position (Adjustment of the bed backrest or whole-bed tilt)
-Head elevation group (30-45 degree angle): head position maintained at 30-45 degree angle
-Supine position group (0-10 degree angle):
Head position, Temperature control
Sponsors
Kawakita Kenya
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with return of spontaneous circulation (ROSC) after cardiac arrest who require intensive care management 2) Unconsciousness after ROSC (Glasgow Coma Scale motor score < 6) 3) 18 years or older
Exclusion criteria
Exclusion criteria: 1) Refusal of intensive care management 2) Extracorporeal cardiopulmonary resuscitation (ECPR) performed as cardiopulmonary resuscitation 3) Known or estimated pregnancy 4) Cardiac arrest (including suspected cases) due to intracerebral hemorrhage, subarachnoid hemorrhage, cerebral infarction, acute aortic dissection, or terminal cancer 5) Known chronic obstructive pulmonary disease with home oxygen therapy 6) Known cerebral performance category (CPC) of 3-4 or overall performance category (OPC) of 3-4 before cardiac arrest 7) Patients with a pre-existing do-not-attempt-resuscitation (DNAR) order at the time of cardiac arrest. 8) Anticipated early death 9) Consent not obtained or withdrawn by the participant or surrogate 10) Other reasons deemed inappropriate for participation by the investigator or subinvestigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality at 90 days | — |
Secondary
| Measure | Time frame |
|---|---|
| -All-cause in-hospital mortality -Modified Rankin Scale (mRS) at hospital discharge, 30 days, and 90 days after admission | — |
Contacts
Public ContactYoko Kataoka
Kagawa University Hospital
Outcome results
None listed