sepsis sepsis
Conditions
Interventions
Administer a synbiotic product to the patient
Sponsors
Saijo Saki
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients diagnosed with sepsis and admitted to the ICU, in whom enteral nutrition was initiated within 24 hours of ICU admission
Exclusion criteria
Exclusion criteria: Patients who died within 24 hours after ICU admission Pregnant or breastfeeding women Patients with conditions that contraindicate enteral nutrition (intestinal obstruction, gastrointestinal perforation) Patients who had been continuously using synbiotic products prior to the study Patients with a known allergy to synbiotic products If the patient (or their legal representative) refuses to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-intensive care syndrome (PICS) within 30 days after ICU discharge, including physical, cognitive, and psychological impairments | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of post-intensive care syndrome (PICS) Length of ICU stay Length of hospital stay 28-day mortality rate Incidence of infections (e.g., ventilator-associated pneumonia [VAP], catheter-related bloodstream infection [CRBSI], urinary tract infection) Duration of antibiotic use Gastric residual volume Bowel conditions (frequency and amount of defecation, stool characteristics) Changes in blood inflammatory markers (e.g., C-reactive protein [CRP]) | — |
Contacts
Public ContactSaki Saijo
Tokushima University Graduate School
Outcome results
None listed