Expression of genes associated with type 2 inflammation in eosinophilic sinusitis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1060230017

Enrollment

200

Registered

2023-05-21

Start date

2023-05-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasal sinus disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient Groups 1. patients who have been determined to be candidates for surgical treatment of eosinophilic sinusitis 2. Adult patients who have listened to the explanation of the study and given their consent. Control group 1. patients with rhinosinus diseases other than eosinophilic sinusitis for which surgical treatment is indicated 2. adult patients who have listened to the study description and have given their consent

Exclusion criteria

Exclusion criteria: 1. Patients under 18 years old 2. pregnant women

Design outcomes

Primary

Measure	Time frame
Gene expression associated with nasal mushrooms and type 2 inflammation of the nasal sinus mucosa collected from patients' nasal sinus tissue will be analyzed for patients with eosinophilic sinusitis and other patients. Gene expression analysis will be identified using real-time PCR.	—

Contacts

Public ContactHitoshi Shono

Tokushima university hospital

hshono722@gmail.com+81-9075736644

Outcome results