Development and validation for visualisation of the non-linear correlation between age and clinical outcome in patients with aneurysmal subarachnoid haemorrhage

Development and validation of a generalised additive model for visualisation of the non-linear correlation between age and clinical outcome in patients with aneurysmal subarachnoid haemorrhage

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-jRCT1060210092

Enrollment

8000

Registered

2022-03-30

Start date

2000-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aneurysmal subarachnoid hemorrhage subarachnoid hemorrhage, visualization, prediction model, validation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients age between 18 and 89 years old, pre-event modified Rankin Scale score 0-2, saccular aneurysm, normal size aneurysm, and ruptured saccular single aneurysm and patients treated via surgical clipping or endovascular coiling within 3 days after onset.

Exclusion criteria

Exclusion criteria: patients with dissecting aneurysms, infectious or traumatic pseudo-aneurysms, giant aneurysms, or aneurysms of an unknown or unrecorded origin; patients with missing data for any of the analyzed variables; patients who only received cerebrospinal fluid drainage, conservative management, wrapping, trap and bypass surgery for unusual aneurysms, or proximal parent artery occlusion; patients with a pre-event modified Rankin Scale score 2-5 and patients who were not treated within 3 days after onset.

Design outcomes

Primary

Measure	Time frame
modified Rankin Scale (mRS) score at discharge	—

Contacts

Public ContactFUSAO IKAWA

Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo, Shimane, Japan

fikawa-nsu@umin.ac.jp+81-853-22-5111-7320

Outcome results