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Feasibility study of allogeneic mesenchymal stem cell therapy in patients with hypophosphatase

Feasibility study of allogeneic mesenchymal stem cell therapy in patients with hypophosphatasia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-jRCT1060210038
Enrollment
50
Registered
2021-10-05
Start date
2021-10-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypophosphatasia Hypophosphatasia

Interventions

None listed

Sponsors

Taketani Takeshi
Lead Sponsor
PuREC Co. Ltd.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Diagnosed as hypophosphatasia 2) Under 12 years old 3) Have or have been treated with asphotase alpha 4) Written consent of the surrogate has been obtained for participation in this study.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

MeasureTime frame
HLA matching between commartial bone marrow donor database and participant

Secondary

MeasureTime frame
HLA matching between donor database of Japan Marrow Donor Program and participant

Contacts

Public ContactTakeshi Taketani

Shimane University

ttaketani@med.shimane-u.ac.jp+81-853-20-2220

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026