Effects of tastant on salivation flow.

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1060210036

Enrollment

Registered

2021-10-01

Start date

2021-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xerostomia Xerostomia

Interventions

Sustained administration of tastant.The taste solutions are monosodium inosinate, monosodium glutamate, aspartame, sucralose, and acesulfame K. A very small amount of each solution(0.04ml/min) is dro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults over 20 years old of Okayama University School of Dentistry and staff members of Okayama University Hospital

Exclusion criteria

Exclusion criteria: Persons with a history of chemotherapy and radiation therapy for endocrine, immunological disease, liver damage, kidney damage or head and neck cancer and cold and Zinc deficiency and Those receiving medication that may have a direct effect on thirst and those who have saliva of 2g or less when stimulating the Saxon test.

Design outcomes

Primary

Measure	Time frame
Changes in saliva flow over time.	—

Secondary

Measure	Time frame
Subjective evaluation of taste intensity	—

Contacts

Public ContactSUGIMOTO HIKARU

Okayama University Hospital

sugimoto.hika@s.okayama-u.ac.jp+81-862356687

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026