A double-blind, randomized, controlled trial to verify the efficacy of elastic compression stockings for acute proximal deep vein thrombosis

A double-blind, randomized, controlled trial to verify the efficacy of elastic compression stockings for acute proximal deep vein thrombosis - COMPRESSION Trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1052260045

Enrollment

200

Registered

2026-05-12

Start date

2026-05-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep vein thrombosis Deep vein thrombosis, Post-thrombotic syndrome

Interventions

Elastic compression stockings

D053828

Compression, Stockings

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed with first acute symptomatic proximal deep vein thrombosis by imaging examinations

Exclusion criteria

Exclusion criteria: Patients who cannot use elastic compression stockings Patients with a life expectancy of 6 months or less Patients who have undergone thrombolytic therapy Patients who have undergone invasive thrombectomy, including endovascular therapy Patients who are deemed inappropriate by their attending physician

Design outcomes

Primary

Measure	Time frame
Post-thrombotic syndrome at 2 years	—

Secondary

Measure	Time frame
Pain assessment at 3 months Calf and ankle circumference at 3 months Recurrent venous thromboembolism during follow-up Major bleeding during follow-up All-cause mortality during follow-up Adverse events attributable to compression stockings during follow-up Adherence to compression stockings during follow-up	—

Contacts

Public ContactYugo Yamashita

Kyoto University Hospital

yyamashi@kuhp.kyoto-u.ac.jp+81-75-751-4255

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026