Tourette Syndrome Tourette Syndrome
Conditions
Interventions
Use of oral splints, MR imaging
Sponsors
Shimamoto Hiroaki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy Subjects (30 participants) Gender does not matter. Must be right-handed as determined by a handedness test. Individuals without taste abnormalities and those not meeting diagnostic criteria for Tourette syndrome. 2. Tourette Syndrome Subjects (30 participants) Patients currently receiving treatment or newly presenting at the Division of Special Care Dentistry, the University of Osaka Dental Hospital. Must meet DSM-5 diagnostic criteria for Tourette syndrome and be right-handed as determined by a handedness test.
Exclusion criteria
Exclusion criteria: 1. Individuals who are unable to provide written informed consent themselves or through a legally authorized representative (in the case of minors), even after sufficient explanation of the study. 2. Individuals diagnosed with Attention-Deficit/Hyperactivity Disorder, Schizophrenia Spectrum and Other Psychotic Disorders, Delirium, Dementia, Amnestic Disorders and Other Neurocognitive Disorders, Substance-Related and Addictive Disorders, Eating Disorders, or Personality Disorders according to the DSM-5. 3. Individuals with physical illnesses requiring strict dietary management or other severe physical conditions. 4. Women who are pregnant, may be pregnant, or are breastfeeding. 5. Individuals for whom an urgent change in treatment plan is anticipated due to unstable mental or physical conditions. 6. Individuals with metallic implants or other contraindications to MRI. 7. Other individuals deemed unsuitable for participation by the attending physician or study investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MR images | — |
Contacts
Public ContactYuka Uchimoto
The University of Osaka Dental Hospital
Outcome results
None listed