The research aboout the domain commonality and specificity between the motivational aberrant salience and psychiatric symptoms

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1052240225

Enrollment

100

Registered

2024-12-23

Start date

2024-12-23

Completion date

Unknown

Last updated

2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia, Schizoaffective disorder, Delusional disorder, Bipolar Disorder, Depressive Disorder mental illness

Interventions

Patient group and healthy control group: 7 Tesla MRI with cognitive tasks, 60 to 90 minutes per session

D019047

7T MRI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a) Patient group: Patients aged 16 years or older with schizophrenia (F2 in ICD-10, including schizophrenia, schizoaffective disorder, delusional disorder, etc.) and mood disorders (F3 in ICD-10, including bipolar disorder and depression) b) Healthy control group: People aged 16 years or older who have not been diagnosed with any clear mental illness, including pre-existing conditions

Exclusion criteria

Exclusion criteria: Those with neurological disorders or disorders that affect the metabolism of the central nervous system Those who are unable to give consent due to medical conditions, etc. Those who meet the contraindications for MRI imaging

Design outcomes

Primary

Measure	Time frame
Reaction speed, probability estimation, and fMRI-measured brain activity during the presentation of a modified Monetary Incentive Delay (MID) task	—

Secondary

Measure	Time frame
ASI, PDI, QPE, PLE, BIS/BAS and PANSS scores	—

Contacts

Public ContactYinan Li

Graduate School of Medicine, Kyoto University

kupsy.research@gmail.com+81-75-751-4947

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026