esophageal squamous carcinoma Narrow Band Imaging, iodine staining, esophageal squamous carcinoma, Endoscopic Submucosal Dissection
Conditions
Interventions
<Period
From the date of publication of the jrct to December 31, 2026
<Targets
Patients scheduled for endoscopic submucosal dissection (ESD) for superficial esophageal cancer.
<Allocation
Patients wil
randomized enrollment and assigned to two groups
Sponsors
Fukunaga Shusei
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following selection criteria and do not meet any of the exclusion criteria will be included in this study. Patients with superficial esophageal cancer 1. patients scheduled to undergo ESD between the jRCT publication date and December 2026 2. patients who are able to undergo endoscopic observation 2-3 months after the date of publication of the jRCT 3. Patients who are at least 20 years of age at the time of the first ESD treatment
Exclusion criteria
Exclusion criteria: 1. Patients with superficial esophageal cancer of the entire circumference 2. patients who have been previously enrolled in this study 3. pregnant, possibly pregnant, or lactating 4. patients with psychosis or psychiatric symptoms that would make it difficult for them to participate in the study 5. patients with iodine allergy 5. patients who are allergic to iodine and have difficulty with iodine spraying 6. patients scheduled to be treated for advanced cancer of other organs within 3 months 7. patients with a lesion in close proximity to the study site 8. other patients who are deemed inappropriate for the study by the treating physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of correct diagnosis of tumor extent | — |
Secondary
| Measure | Time frame |
|---|---|
| Aspiration pneumonia rate, marking time, treatment time, and post-resection ulcer base circumference, area of resection specimen, percentage of positive horizontal margins, percentage of post-ESD stenosis, percentage of cancer remnant at ESD ulcer healing (2-3 months later), risk factors for misdiagnosis | — |
Contacts
Public ContactMitsuhiro Kono
Osaka Metropolitan University Hospital
Outcome results
None listed