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Study of brain activity changes by electrical stimulation on scalp and rehabilitation

Research on the neural basis of functional recovery from disability using transcranial direct current stimulation and rehabilitation in neurological diseases

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCT1052220196
Enrollment
200
Registered
2023-03-17
Start date
2023-03-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Nervous System Diseases neurological disorders

Interventions

Sponsors

Hanakawa Takashi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 Patients who are 18years of age or older at the time of consent to participate in the study and are undergoing medical treatment at the outpatient or inpatient department of neuology or otorhinolaryngology, Kyoto University Hospital or Murata Hospital 2 Patients who have developed cerebrovascular disorders, neurodegenerative diseases, involuntary movement diseases, neuroinflammatory diseases, central neurological disorders, or traumatic central neurological disorders, and for whom the diagnosis has been established by neurological findings, imaging findings 3 6 days or more after the onset of symptoms, or 6 days or more after the recurrence of symptoms 4 Patients suffering from any of the following disorders due to neurological diseases: motor disorder, higher brain dysfunction, language disorder, and dysphagia 5 Patients who have given a full explanation and have given written consen from the person or proxy if written consent from the person is difficult to obtain

Exclusion criteria

Exclusion criteria: 1 5 days or more before the onset of symptoms, or 5 days or more before the recurrence of symptoms 2 Patients who are difficult to communicate due to significant hearing impairment 3 Patients who have a cardiac pacemaker 4 Ptients who has metals in the body which cannot be confirmed to be non-magnetic 5 Those who are judged inappropriate as a participant by the "Transcranial Magnetic Stimulation Test / Pre-Checklist" and "MR Test Pre-Checklist". 6 Those who are with claustrophobia 7 Other patients who are deemed unsuitable for the safe conduct of this study, such as those who are unable to remain at rest.

Design outcomes

Primary

MeasureTime frame
Activity changes in EEG (analysis of EEG amplitude, frequency analysis)

Secondary

MeasureTime frame
Amplitude values in each frequency band of MEG Changes in cerebral blood flow during the task and at rest by fMRI Motor evoked potential by TMS Evaluation of motor and cognitive functions

Contacts

Public ContactTomoya Gyoda

Kyoto university

reha_neuro@kuhp.kyoto-u.ac.jp+81-75-751-3695

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026