Effect of resistance training on skeletal muscle quality and brain function for patients with knee osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1052210143

Enrollment

Registered

2021-12-26

Start date

2021-12-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Patients undergo twice per week resistance training programme for a twelve-week. Resistance training of two types are applied

Power training (high speed) and conventional training (low speed). These interventions are performed on the quadriceps with a weight.

D055070

Resistance training

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Woman diagnosed with knee OA based on X-ray findings by a doctor Patients who have the ability to walk without assistive devices

Exclusion criteria

Exclusion criteria: Patients with rheumatoid arthritis, spontaneous osteonecrosis of the knee. Patients with a surgical or fracture history for lower limbs. Patients with cardiovascular disorders that significantly affect gait function. Patients with a history for mental and neurological disorders. Patients who have contraindications for MRI measurement.

Design outcomes

Primary

Measure	Time frame
Muscle quarity and quantity	—

Secondary

Measure	Time frame
Muscle strength, Knee function, Gait function	—

Contacts

Public ContactMasashi Taniguchi

Kyoto University

taniguchi.masashi.7a@kyoto-u.ac.jp+81-75-751-3964

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026